Once you delete a hotfix file, you can no longer uninstall the hotfix. Here's how to delete them:
1. Go to Start>> My Computer
2. Double click your hard drive where your Windows installation resides (usually C:\)
3. Double click the WINDOWS folder
4. The files in blue ($NTUninstallKBxxxxxx$) are the hotfix uninstall files.
5. Right click a selected file and choose delete.